Celebrating Silver Jubilee 2016
Department of Biotechnology bt@niper.ac.in

The laboratories in the department are working in the areas of cell biology, biochemistry, immunology, molecular biology, microbiology, parasitology, cell culture, and membrane drug interaction. The department is actively pursuing research in the following areas.

  • Targeting signal transduction involved in microbial drug resistance
  • Identification of new target protein(s) in insulin mediated signal transduction and in insulin resistance
  • Enzyme drug interaction of medically important enzymes (Xanthine oxidase, HMG-CoA reductase etc.)
  • Membrane drug interaction for better understanding of tissue specific drug targeting
  • Proteomic analysis of yeast and mammalian cell to identify genes that regulate aging and knowledge based pathway building using informatics to understand set of circuits involved human longevity
  • Applied recombinant DNA technology for production of commercially important biochemicals
Projects (Completed and Ongoing)
  • Regulation of multiple drug resistance by protein phosphorylation in Leishmani donovani
  • Regulation of skeletal muscle thick filament assembly by protein phosphorylation and insulin signaling
  • Identification of phosphorylation regulated insulin-signaling protein in differentiated skeletal muscle cells in culture
  • Analyses of DNA complexes and their interaction with drugs in wild type and arsenite resistant Leishmania donovani
  • Studies on the multi-substrate interaction kinetics with natural & anti cancer drug substrates on xanthine oxidase